Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RXRG | P48443 | 6/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785505 | 0.74 | RXRA (0.50) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL43496 | 0.69 | GABRA1 (0.43) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL3536621 | 0.69 | TSHR (0.44) | CYP2D6CYP3A4TSHRCETP | |
| SCHEMBL3537961 | 0.68 | CYP2C19 (0.41) | CYP2C19TSHRCETP | |
| SCHEMBL64462 | 0.68 | RXRB (0.46) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL18995910 | 0.68 | CETP (0.47) | CYP3A4CETP | |
| SCHEMBL7931675 | 0.67 | GABRA1 (0.44) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL20815361 | 0.67 | LMNA (0.45) | RXRARXRBRXRGGABRA1GABRB2 | |
| SCHEMBL1632396 | 0.67 | TDP1 (0.55) | CYP2D6CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL88554 | 0.66 | RXRA (0.50) | RXRARXRBRXRGGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580559-A | Dental cement composition, kit of parts and use thereof | 3M创新有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112055579-B | One-component dental adhesive composition for fixing dental composite materials | 3M创新有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-111315341-B | Dental composition with high E-modulus | 3M创新有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-112055579-A | One-component dental adhesive composition for fixing dental composite material | 3M创新有限公司 | 2020-12-08 | — | — | CN | disclosed |
| US-8129444-B2 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| EP-1387657-B1 | SELF-ADHESIVE DENTAL MATERIALS | 3M ESPE AG (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7456232-B2 | Use of branched polyacids in dental compounds | 3M ESPE AG (DE) | 2008-11-25 | — | — | US | disclosed |
| EP-1337222-B1 | UTILIZATION OF POLYACIDS HAVING A TIGHT MOLAR MASS DISTRIBUTION | 3M ESPE AG (DE) | 2008-03-26 | — | — | EP | disclosed |
| EP-1337221-B1 | USE OF BRANCHED POLYACIDS IN DENTAL COMPOUNDS | 3M ESPE AG (DE) | 2007-08-08 | — | — | EP | disclosed |
| US-7141616-B2 | Radically curable urethane prepolymers and their use in dental materials | 3M ESPE AG (DE) | 2006-11-28 | — | — | US | disclosed |
| US-20040110864-A1 | Self-adhesive dental materials | 3M ESPE AG (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-1242493-B1 | RADICALLY CURABLE URETHANE PREPOLYMERS AND THEIR USE IN DENTAL MATERIALS | ESPE DENTAL AG (DE) | 2003-10-08 | — | — | EP | disclosed |
| EP-1222220-B1 | FILLER FOR PLASTIC FORMULATIONS BASED ON POLYURETHANE | 3M ESPE AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| EP-0717977-B1 | Fluoride releasing dental composite material | 3M ESPE AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-20030008967-A1 | Radically curable urethane prepolymers and their use in dental materials | 3M INNOVATIVE PROPERTIES COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-5968998-A | ADDITIONALLY CONTAINING SPECIFIED UNSATURATED ARYL COMPOUND TO LENGTHEN SETTING TIME | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1999-10-19 | — | — | US | disclosed |
| US-5824720-A | DI OR MULTI(METH)ACRYLATES, INITIATORS, ACTIVATORS, FILLERS AND FLUORIDE COMPLEXES FOR DENTAL FILLING | THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR INDUSTRIELLE SCHUTZRECHTE (DE) | 1998-10-20 | — | — | US | disclosed |
| US-5583164-A | FREE RADICAL POLYMERIZATION; DELAY CURING | ESPE STIFTUNG & CO. PRODUKTIONS-UND VERTRIEBS KG (DE) | 1996-12-10 | — | — | US | disclosed |
| EP-0717977-A2 | Fluoride releasing dental composite material | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1996-06-26 | — | — | EP | disclosed |
| EP-0374824-B1 | DENTAL COMPOSITIONS CONTAINING BIFUNCTIONAL ACRYLIC OR METHACRYLIC ACID ESTERS | THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) | 1993-09-22 | — | — | EP | disclosed |