Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 8/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 8/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 8/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286288 | 0.81 | FAAH (0.39) | PREPELANESIGMAR1ACE2FKBP1A | |
| SCHEMBL7279122 | 0.80 | F2 (0.37) | PREP | |
| SCHEMBL7278813 | 0.80 | F2 (0.37) | PREPPRSS1PRSS2PRSS3ELANE | |
| SCHEMBL7276163 | 0.78 | ELANE (0.39) | PREPELANE | |
| SCHEMBL7276586 | 0.77 | SIGMAR1 (0.39) | PREPELANESIGMAR1ACE2FKBP1A | |
| SCHEMBL9744946 | 0.77 | ELANE (0.47) | ELANE | |
| SCHEMBL7289208 | 0.77 | ELANE (0.47) | ELANEPOLB | |
| SCHEMBL7004719 | 0.77 | NPC1 (0.37) | PREPELANEPOLBFKBP1A | |
| SCHEMBL7288778 | 0.75 | ELANE (0.34) | ELANE | |
| SCHEMBL7285956 | 0.75 | TSHR (0.38) | PREPELANESIGMAR1ACE2FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849605-B1 | Inhibitors of serine protease activity, methods and compositions for treatment of viral infections | THE TRUSTEES OF UNIVERSITY TECHNOLOGY CORPORATION (US) | 2005-02-01 | — | — | US | claimed |