Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.44 |
| ▸ | ME1 | P48163 | 1/20 | 0.44 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169028 | 0.74 | PTGS2 (0.53) | SMN1; SMN2PTGS2MAOANPC1TP53 | |
| SCHEMBL20323016 | 0.74 | EDNRA (0.44) | SMN1; SMN2PTGS2MAOANPC1TP53 | |
| SCHEMBL17971687 | 0.73 | ME2 (0.54) | SMN1; SMN2PTGS2MAOANPC1TP53 | |
| SCHEMBL6454698 | 0.72 | KDM1A (0.40) | PTGS2NPC1RAB9AHPGDKDM1A | |
| SCHEMBL6733562 | 0.69 | CA1 (0.79) | SMN1; SMN2NPC1TP53MAPTRAB9A | |
| SCHEMBL9151672 | 0.69 | CA1 (0.79) | SMN1; SMN2NPC1TP53MAPTRAB9A | |
| SCHEMBL197522 | 0.69 | CA1 (0.79) | SMN1; SMN2NPC1TP53MAPTRAB9A | |
| SCHEMBL6568720 | 0.68 | MEN1 (0.46) | SMN1; SMN2MAOANPC1RAB9AHPGD | |
| SCHEMBL28890215 | 0.67 | CA1 (0.73) | SMN1; SMN2NPC1TP53MAPTRAB9A | |
| Iodide SCHEMBL28861996 | 0.67 | CA1 (0.73) | SMN1; SMN2NPC1TP53MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171306-A1 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2005-08-04 | — | — | US | disclosed |
| US-6919292-B2 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2005-07-19 | — | — | US | disclosed |
| US-20020120160-A1 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | TOSOH CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| JP-2000053599-A | PENTAARYLCYCLOPENTADIENE COMPOUNDS AND PRODUCTION | MIURA MASAHIRO | 2000-02-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171306-A1 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | PORCN, FDFT1, CPNE4 | SMN1; SMN2 2692/4885PTGS2 984/4885MAOA 267/4885 |
| US-20020120160-A1 | Transition metal compound, coordinative compound, catalyst for polymerization of olefin, and process for polymerization of olefin using the catalyst | PORCN, FDFT1, CPNE4 | SMN1; SMN2 2692/4885PTGS2 984/4885MAOA 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.