Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527824 | 0.83 | TOP2A (0.42) | ALDH1A1MAPTRAB9AGAAKMT2A | |
| Ethyl Acetate SCHEMBL1068768 | 0.80 | CA12 (0.44) | ALDH1A1TSHRMAPTRAB9APIN1 | |
| SCHEMBL1365239 | 0.77 | NR4A2 (0.39) | PIN1 | |
| SCHEMBL13857953 | 0.74 | PSMD14 (0.42) | PIN1 | |
| SCHEMBL288687 | 0.74 | PIN1 (0.35) | PIN1 | |
| SCHEMBL288688 | 0.74 | ELANE (0.43) | ALDH1A1TSHRADRA1AACHEPIN1 | |
| SCHEMBL3356073 | 0.74 | NR4A2 (0.38) | ALDH1A1MAPTRAB9AGAAKMT2A | |
| SCHEMBL926877 | 0.74 | HSD17B10 (0.36) | ALDH1A1TSHRMAPTGAAKMT2A | |
| SCHEMBL2005830 | 0.74 | PIN1 (0.40) | ALDH1A1RAB9AGAAKMT2APIN1 | |
| SCHEMBL1881059 | 0.74 | PIN1 (0.40) | ALDH1A1TSHRMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137541-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-118420543-A | Tumor inhibitor targeting EP300 mutation and application thereof | 上海美得诺瓦生物医药科技有限公司 | 2024-08-02 | — | — | CN | disclosed |
| US-20230062100-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | disclosed |
| CN-115210225-A | Substituted aminoquinolones as immuno-activated DGKALPHA inhibitors | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |
| EP-4065570-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | Bayer Aktiengesellschaft (DE) | 2022-10-05 | — | — | EP | disclosed |
| US-11447471-B2 | α,β-unsaturated amide compound | KYOWA KIRIN CO., LTD. (JP) | 2022-09-20 | — | — | US | disclosed |
| EP-3444238-B1 | PROCESS FOR PREPARING DIFLUOROMETHYLENE COMPOUNDS | SATO PHARMA (JP) | 2021-12-08 | — | — | EP | disclosed |
| US-20210155612-A1 | Alpha,Beta-UNSATURATED AMIDE COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2021-05-27 | — | — | US | disclosed |
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2020-11-26 | — | — | US | disclosed |
| EP-3712129-A1 | ALPHA, BETA-UNSATURATED AMIDE COMPOUND | Kyowa Kirin Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |
| WO-1997022619-A2 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1997-06-26 | — | — | WO | disclosed |
| WO-1995035308-A1 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-12-28 | — | — | WO | disclosed |
| EP-0681216-A1 | Photographic colour developing process | Agfa-Gevaert AG (DE) | 1995-11-08 | — | — | EP | disclosed |
| EP-0681216-A1 | Photographic colour developing process | Agfa-Gevaert AG (DE) | 1995-11-08 | — | — | EP | disclosed |
| US-5114462-A | Herbicides as plant growth regulators, phenoxypropionic acid esters and derivatives | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | disclosed |
| US-5078780-A | Plant safening agents for use with herbicides | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | disclosed |
| US-4944790-A | PLANT SAFENING AGENTS FOR USE WITH CERTAIN HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| US-4579865-A | ANTIISCHEMIC, HYPOGLYCEMIC AGENTS | USV PHARMACEUTICAL CORP. (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0116938-A1 | Benzoheterocyclic carbamates | USV PHARMACEUTICAL CORPORATION (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4009038-A | CYAN COUPLER, A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155612-A1 | Alpha,Beta-UNSATURATED AMIDE COMPOUND | NR1H2, NR1H3, RXRA | ALDH1A1 675/4885TSHR 971/4885MAPT 4512/4885 |
| US-11447471-B2 | α,β-unsaturated amide compound | NR1H2, RXRA, RXRB | ALDH1A1 683/4885TSHR 733/4885MAPT 4590/4885 |
| US-20230062100-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | DGKK, DGKG, DGKA | ALDH1A1 4050/4885TSHR 3329/4885MAPT 4822/4885 |
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | ITGB6, ITGA6, ITGAV | ALDH1A1 3118/4885TSHR 1760/4885MAPT 4434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.