Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28657136 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL787461 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28678731 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL17389368 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2157200 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL23234052 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7069870 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2424 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118079999-B | Trans-capsule catalyst and preparation method and application thereof | Shandong Energy Group Coal Gasification New Materials Technology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121136543-B | Wear-resistant formaldehyde-removing artistic coating and preparation method thereof | Foshan weizbo coating Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122076405-A | Adsorbent based on MOF material and processing technology thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076969-A | Powder alloy for preparing automobile gear and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122078027-A | Flexible connecting band of wearable electronic equipment | — | 2026-05-26 | — | — | CN | claimed |
| CN-122076400-A | Heterogeneous metal-organic framework domain-limited polyaniline composite adsorbent and preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-20260139354-A1 | METHODS OF IMPROVING ELECTRODES FOR LIQUID ALKALINE WATER ELECTROLYZERS | THE REGENTS OF THE UNIV OF CALIFORNIA (US) | 2026-05-21 | — | — | US | claimed |
| CN-122039138-A | Method for preparing Cr-NiSe2/NF hydrogen evolution catalyst by high-temperature selenization and application thereof | 北京工业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122039125-A | Wood-derived carbon self-supporting transition metal core-shell hydrogen evolution catalyst and preparation method thereof | 广西大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122037641-A | Corrosion-resistant protective varnish for automobile air inlet grille and preparation method thereof | 长春富维高新汽车饰件有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20030202933-A1 | Method for producing high surface area chromia materials for catalysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-10-30 | — | — | US | claimed |
| US-6514896-B1 | Catalyst composition and a process of using thereof | PHILLIPS PETROLEUM COMPANY | 2003-02-04 | — | — | US | claimed |
| US-6300272-B1 | PRODUCING CHROMIUM CATALYSTS ON SILICA FOR POLYMERIZATION OF MONOMERS SUCH AS ETHYLENE | FINA RESEARCH, S.A. (BE) | 2001-10-09 | — | — | US | claimed |
| EP-1090042-A1 | CATALYSTS FOR POLYETHYLENE PRODUCTION AND USE THEREOF | FINA RESEARCH S.A. (BE) | 2001-04-11 | — | — | EP | claimed |
| US-6110859-A | Hybrid catalyst system for converting hydrocarbons and a method of making and using such catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 2000-08-29 | — | — | US | claimed |
| US-6090992-A | COMPRISING ALUMINA, AT LEAST ONE CARBURIZED TRANSITION METAL, AND AT LEAST ONE HALOGEN COMPONENT. | PHILLIPS PETROLEUM COMPANY (US) | 2000-07-18 | — | — | US | claimed |
| US-6037294-A | ACID-TREATING ZEOLITE, ION-EXCHANGING WITH ZINC AND AT LEAST ONE GROUP 6B METAL, THEN STEAM TREATING | PHILLIPS PETROLEUM COMPANY (US) | 2000-03-14 | — | — | US | claimed |
| WO-1999064473-A1 | CATALYSTS FOR POLYETHYLENE PRODUCTION AND USE THEREOF | FINA RESEARCH S.A. (BE) | 1999-12-16 | — | — | WO | claimed |
| EP-0962468-A1 | Catalysts for polyethylene production and use thereof | FINA RESEARCH S.A. (BE) | 1999-12-08 | — | — | EP | claimed |
| US-4472531-A | CHROMIUM OXIDE ON SILICA SUPPORT, FROM DECOMPOSITION OF CHROMIUM NITRATE IN SILICA GEL | NATIONAL PETRO CHEMICALS CORPORATION (US) | 1984-09-18 | — | — | US | claimed |