Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28657136 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28678731 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL17389368 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2157200 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL646247 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL23234052 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL7069870 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119774633-A | Conductive Y zeolite molecular sieve and preparation method and application thereof | 西北工业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-118880382-A | Trimetallic nano anode electrocatalyst and preparation method and application thereof | 华中科技大学 | 2024-11-01 | — | — | CN | claimed |
| CN-118771468-A | Preparation method and application of multielement bulk phase doped modified lithium nickel manganese oxide positive electrode material | 中国科学院金属研究所 | 2024-10-15 | — | — | CN | claimed |
| CN-118718754-A | Modified filtering membrane, preparation method and application thereof | 上海科技大学 | 2024-10-01 | — | — | CN | claimed |
| CN-118599135-A | Method for regulating and controlling metal organic framework material structure by steam and valence-variable metal ions | 福州大学 | 2024-09-06 | — | — | CN | claimed |
| CN-117790774-A | Chromium-doped lithium manganate positive electrode material, preparation method thereof and electrochemical energy storage device | 江西赣锋锂电科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117531491-A | Solid phase extraction membrane and preparation method and application thereof | 中山大学 | 2024-02-09 | — | — | CN | claimed |
| CN-116553620-A | High-entropy spinel oxide material and preparation method and application thereof | 武汉理工大学 | 2023-08-08 | — | — | CN | claimed |
| CN-116440910-A | Preparation method and application of potassium ion doped cobalt chromate solid solution | 常州大学 | 2023-07-18 | — | — | CN | claimed |
| CN-114618441-B | Controllable preparation method of MIL material and application of MIL material in separation and enrichment of polyalcohol | 中国科学院大连化学物理研究所 | 2023-07-04 | — | — | CN | claimed |
| US-8491861-B2 | Synthetic process for preparation of high surface area electroactive compounds for battery applications | ELTRON RESEARCH, INC. (US) | 2013-07-23 | — | — | US | claimed |
| US-20130153821-A1 | SYNTHETIC PROCESS FOR PREPARATION OF HIGH SURFACE AREA ELECTROACTIVE COMPOUNDS FOR BATTERY APPLICATIONS | ELTRON RESEARCH, INC. (US) | 2013-06-20 | — | — | US | claimed |
| CN-102617646-A | Preparation method of nanoscale metal organic framework materials | NINGBO INST MAT TECH & ENG CAS | 2012-08-01 | — | — | CN | claimed |
| US-6514896-B1 | Catalyst composition and a process of using thereof | PHILLIPS PETROLEUM COMPANY | 2003-02-04 | — | — | US | claimed |
| WO-2001000560-A1 | PROCESS FOR PREPARING AROMATIC CARBONATES | LG CHEMICAL LTD. (KR) | 2001-01-04 | — | — | WO | claimed |
| EP-0422105-B1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1994-09-07 | — | — | EP | claimed |
| US-5114702-A | Method of making metal oxide ceramic powders by using a combustible amino acid compound | BATTELLE MEMORIAL INSTITUTE (US) | 1992-05-19 | — | — | US | claimed |
| EP-0422105-A4 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | — | 1992-01-08 | — | — | EP | claimed |
| EP-0422105-A1 | METAL OXIDE CERAMIC POWDERS AND METHODS OF MAKING SAME. | BATTELLE MEMORIAL INSTITUTE (US) | 1991-04-17 | — | — | EP | claimed |
| WO-1989012027-A1 | METAL OXIDE CERAMIC POWDERS AND THIN FILMS AND METHODS OF MAKING SAME | BATTELLE MEMORIAL INSTITUTE (US) | 1989-12-14 | — | — | WO | claimed |