Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 4/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463648 | 0.83 | CTSS (0.39) | CCR1MMP2MMP1MMP3SMN1; SMN2 | |
| SCHEMBL6466334 | 0.81 | CCR1 (0.39) | CCR1MMP2MMP1MMP3MEN1 | |
| SCHEMBL6465743 | 0.78 | CTSS (0.40) | CCR1KMT2ACTSSCTSL | |
| SCHEMBL6472179 | 0.65 | MMP3 (0.44) | MMP2MMP1MMP3CTSSCTSL | |
| SCHEMBL6462284 | 0.64 | PTPN1 (0.39) | CCR1 | |
| SCHEMBL386637 | 0.60 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5968343 | 0.58 | TAAR1 (0.48) | NPC1RAB9AKMT2A | |
| SCHEMBL386760 | 0.57 | HSPA5 (0.46) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18726535 | 0.57 | HSPA5 (0.46) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27520194 | 0.57 | HRH3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |