SCHEMBL646374

SCHEMBL646374

CCOC(=O)CCC(=O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.57
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
CYP4F2 P78329 2/20 0.51
CYP4A11 Q02928 2/20 0.51
ELANE P08246 1/20 0.49
PPID Q08752 1/20 0.47
MEN1 O00255 1/20 0.47
TOP2A P11388 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446504 0.93 CYP4F2 (0.56) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
SCHEMBL31186939 0.93 EGFR (0.54) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
SCHEMBL20565144 0.91 PRSS1 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
SCHEMBL20563918 0.91 PRSS1 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
SCHEMBL20564506 0.91 PRSS1 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
SCHEMBL20564734 0.91 PRSS1 (0.57) SMN1; SMN2KMT2AALDH1A1MAPTCYP4F2
Diphenylether SCHEMBL6917810 0.87 SMN1; SMN2 (0.58) SMN1; SMN2KMT2AALDH1A1MAPTLMNA
Ethyl Propionate SCHEMBL7262212 0.86 ELANE (0.51) SMN1; SMN2KMT2AALDH1A1MAPTLMNA
SCHEMBL43742 0.86 KMT2A (0.61) SMN1; SMN2KMT2AALDH1A1MAPTLMNA
SCHEMBL27736999 0.86 RXRA (0.50) SMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109266058-B Catalysis method and use method of water-based inorganic nano-coating 湖南凯斯利新材料有限公司 2021-07-16 CN claimed
EP-3625283-B1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE BV (NL) 2025-05-07 EP disclosed
US-11548980-B2 Polyester copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2023-01-10 US disclosed
CN-115109430-A Pigment and preparation method thereof 宁夏彩妍科技有限公司 2022-09-27 CN disclosed
CN-109651887-B Perovskite quantum dot ink and luminescent film 苏州星烁纳米科技有限公司 2022-06-10 CN disclosed
US-20210139645-A1 Polyester Copolymer AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2021-05-13 US disclosed
EP-3625283-A1 POLYESTER COPOLYMER Avantium Knowledge Centre B.V. (NL) 2020-03-25 EP disclosed
EP-2216312-B1 PROCESS FOR PRODUCING ORGANIC COMPOUND M TECHNIQUE CO LTD (JP) 2019-05-01 EP disclosed
WO-2018211132-A1 POLYESTER COPOLYMER AVANTIUM KNOWLEDGE CENTRE B.V. (NL) 2018-11-22 WO disclosed
EP-2184109-B1 METHOD FOR PRODUCING NANOPARTICLES BY FORCED ULTRA-THIN FILM ROTARY PROCESSING M TECHNIQUE CO LTD (JP) 2017-08-23 EP disclosed
US-6723138-B2 UTILIZING MATERIAL MADE IN MINIATURIZED CONTINUOUS REACTOR. CLARIANT INTERNATIONAL LTD. (CH) 2004-04-20 US disclosed
US-20030158410-A1 Chemical synthesis of pigment red 254 in a miniaturized continuous reactor; process control by an integrated circuits CLARIANT INTERNATIONAL LTD. (CH) 2003-08-21 US disclosed
US-6566519-B2 Reacting succinic diester with nitrile CLARIANT INTERNATIONAL LTD. (CH) 2003-05-20 US disclosed
CN-1398270-A Catalyst components for the polymerization of olefins BASELL TECH CO B V (IT) 2003-02-19 CN disclosed
CN-1334730-A Vitronectin receptor antagonists SMITHKLINE BEECHAM CORP (US) 2002-02-06 CN disclosed
US-20020010331-A1 Reacting succinic diester with nitrile CLARIANT GMBH 2002-01-24 US disclosed
CN-1278250-A Vitronectin receptor antagonists SMITHKLINE BEECHAM CORP (US) 2000-12-27 CN disclosed
CN-1249745-A Vitronectin receptor antagonists SMITHKLINE BEECHAM CORP (US) 2000-04-05 CN disclosed
US-5476949-A Pure red hue, high transparency CIBA-GEIGY CORPORATION (US) 1995-12-19 US disclosed
US-4931566-A Process for the preparation of pyrrolo[3,4-c]pyrroles CIBA-GEIGY CORPORATION (US) 1990-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010331-A1 Reacting succinic diester with nitrile SDHA, QDPR, SDHB SMN1; SMN2 1336/4885KMT2A 2122/4885ALDH1A1 790/4885
US-20030158410-A1 Chemical synthesis of pigment red 254 in a miniaturized continuous reactor; process control by an integrated circuits TYR, PPOX, QDPR SMN1; SMN2 4464/4885KMT2A 1012/4885ALDH1A1 625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.