Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LONP1 | P36776 | 2/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.30 |
| ▸ | CTRL | P40313 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465287 | 0.93 | TRPV1 (0.42) | DAGLATRPV1FAAHLONP1 | |
| SCHEMBL6465469 | 0.89 | PPARG (0.35) | DAGLAKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6463841 | 0.83 | C3AR1 (0.37) | KDM4EKMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6475177 | 0.78 | DAGLA (0.47) | DAGLAKDM4EKMT2ATRPV1 | |
| SCHEMBL6467249 | 0.69 | TRPV1 (0.51) | DAGLATRPV1 | |
| SCHEMBL7466136 | 0.67 | FAAH (0.36) | DAGLAFAAH | |
| SCHEMBL6466197 | 0.67 | FAAH (0.36) | DAGLAFAAH | |
| SCHEMBL6466253 | 0.67 | TMPRSS11D (0.38) | TMPRSS11DCTRL | |
| SCHEMBL6466207 | 0.66 | DAGLA (0.46) | DAGLA | |
| SCHEMBL6464323 | 0.65 | DAGLA (0.45) | DAGLAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |