Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LONP1 | P36776 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465287 | 0.87 | TRPV1 (0.42) | DAGLAFAAHLONP1 | |
| SCHEMBL6463841 | 0.82 | C3AR1 (0.37) | TSHRCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6466207 | 0.77 | DAGLA (0.46) | PPARGPPARADAGLATSHR | |
| SCHEMBL7049142 | 0.73 | ANPEP (0.37) | CA2 | |
| SCHEMBL7044813 | 0.71 | KMT2A (0.34) | DAGLATSHRKMT2A | |
| SCHEMBL7466136 | 0.66 | FAAH (0.36) | PPARGPPARADAGLAFAAHSMN1; SMN2 | |
| SCHEMBL6466197 | 0.66 | FAAH (0.36) | PPARGPPARADAGLAFAAHSMN1; SMN2 | |
| SCHEMBL6466253 | 0.64 | TMPRSS11D (0.38) | — | |
| SCHEMBL6464323 | 0.64 | DAGLA (0.45) | DAGLAFAAH | |
| SCHEMBL6462329 | 0.64 | PLA2G4A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |