Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466099 | 0.82 | DAGLA (0.53) | DAGLANPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL6466216 | 0.80 | DAGLA (0.44) | PIM1PIM2AKR1B1PPARGPPARD | |
| SCHEMBL7186564 | 0.74 | MMP1 (0.39) | NPC1RAB9A | |
| SCHEMBL6463984 | 0.73 | DAGLA (0.40) | PIM1PIM2AKR1B1PPARGPPARD | |
| SCHEMBL7730692 | 0.73 | CTSL (0.42) | DAGLAPTPN2PTPN1NPC1RAB9A | |
| SCHEMBL6466221 | 0.72 | DAGLA (0.41) | PIM1PIM2AKR1B1PPARGPPARD | |
| SCHEMBL6466213 | 0.72 | CTSL (0.45) | PIM1PIM2AKR1B1PPARGPPARD | |
| SCHEMBL6207598 | 0.67 | HDAC3 (0.50) | DAGLANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL5703678 | 0.67 | HDAC3 (0.50) | DAGLANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7732434 | 0.67 | CTSL (0.43) | NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |