Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GART | P22102 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466216 | 0.80 | DAGLA (0.44) | DAGLAAKR1B1PIM1PIM2PPARG | |
| SCHEMBL6467431 | 0.77 | RAB9A (0.42) | DAGLAGARTHDAC1HDAC7FAAH | |
| SCHEMBL7049340 | 0.76 | MEN1 (0.39) | HDAC11HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6465893 | 0.74 | GART (0.43) | DAGLAGARTFAAHCES1CTSS | |
| SCHEMBL6466213 | 0.74 | CTSL (0.45) | DAGLAAKR1B1PIM1PIM2EPHX1 | |
| SCHEMBL3639187 | 0.72 | PIM1 (0.55) | DAGLAAKR1B1HDAC11HDAC3HDAC1 | |
| SCHEMBL6463980 | 0.72 | PIM1 (0.38) | DAGLAAKR1B1PIM1PIM2EPHX1 | |
| SCHEMBL6466913 | 0.70 | FAAH (0.41) | DAGLAGARTFAAHCES1CTSS | |
| SCHEMBL6463984 | 0.69 | DAGLA (0.40) | DAGLAAKR1B1HDAC11HDAC3HDAC1 | |
| SCHEMBL7049339 | 0.67 | CTSS (0.53) | DAGLACTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |