Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GART | P22102 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 5/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466913 | 0.79 | FAAH (0.41) | ALDH1A1GARTELANEFAAHCES1 | |
| SCHEMBL6471951 | 0.78 | XDH (0.43) | GARTELANEFAAHCES1DAGLA | |
| SCHEMBL6464297 | 0.78 | DAGLA (0.44) | ELANEFAAHCES1DAGLAXDH | |
| SCHEMBL6466063 | 0.77 | KDM4E (0.41) | ALDH1A1GARTFAAHCES1DAGLA | |
| SCHEMBL7045297 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4E | |
| SCHEMBL6461911 | 0.75 | FAAH (0.42) | GARTFAAHCES1DAGLACTSS | |
| SCHEMBL6465893 | 0.72 | GART (0.43) | GARTELANEFAAHCES1DAGLA | |
| SCHEMBL6463422 | 0.71 | FAAH (0.41) | GARTFAAHCTSS | |
| SCHEMBL6465159 | 0.70 | FAAH (0.44) | ALDH1A1GARTFAAHCES1DAGLA | |
| SCHEMBL7048984 | 0.69 | KDM4E (0.40) | GARTKDM4EPOLBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |