Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 6/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466913 | 0.79 | FAAH (0.41) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL6471951 | 0.78 | XDH (0.43) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL6467431 | 0.78 | RAB9A (0.42) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL7047104 | 0.74 | LMNA (0.45) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL6466221 | 0.74 | DAGLA (0.41) | GARTFAAHCES1DAGLACTSS | |
| SCHEMBL6466063 | 0.73 | KDM4E (0.41) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL6464310 | 0.72 | ALDH1A1 (0.41) | GARTXDHFAAHCES1DAGLA | |
| SCHEMBL6475534 | 0.72 | SMN1; SMN2 (0.39) | GARTELANECTSSRAB9ANPC1 | |
| SCHEMBL6467567 | 0.71 | CTSS (0.38) | GARTXDHELANECTSSRAB9A | |
| SCHEMBL6463422 | 0.71 | FAAH (0.41) | GARTFAAHCTSSRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |