Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 2/20 | 0.39 |
| ▸ | CTRL | P40313 | 2/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.37 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.37 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6064391 | 0.91 | CTSL (0.49) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6466253 | 0.84 | TMPRSS11D (0.38) | CTSLCTSSMMP3PSMB5MMP2 | |
| SCHEMBL6464784 | 0.83 | ANPEP (0.48) | CTSBCTSLCTSSCTSKMMP3 | |
| SCHEMBL6464783 | 0.83 | MMP9 (0.44) | CTSBCTSLCTSSCTSKMMP3 | |
| SCHEMBL6466271 | 0.83 | MMP9 (0.44) | CTSBCTSLCTSSCTSKMMP3 | |
| SCHEMBL6466269 | 0.83 | MMP9 (0.44) | CTSBCTSLCTSSCTSKMMP3 | |
| SCHEMBL6477967 | 0.81 | MMP3 (0.44) | CTSBCTSLCTSSCTSKDAGLA | |
| SCHEMBL6062904 | 0.81 | CTSL (0.50) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6063413 | 0.78 | CTSL (0.50) | CTSBCTSLCTSSCTSK | |
| SCHEMBL6063868 | 0.77 | PSMB5 (0.44) | CTSBCTSLCTSSCTSKDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |