SCHEMBL6470650

SCHEMBL6470650

C=CCOc1ccc(S(=O)(=O)N(C(N)=O)c2ccc(Cc3ccc(N(C(N)=O)S(=O)(=O)c4ccc(OCC=C)cc4)cc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
POLB P06746 1/20 0.43
LMNA P02545 3/20 0.42
MAPT P10636 5/20 0.41
TP53 P04637 4/20 0.41
BMP1 P13497 2/20 0.39
THRB P10828 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HSP90AA1 P07900 1/20 0.38
RECQL P46063 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6467529 0.84 CNR2 (0.42) CA12CA1CA2CA9LMNA
SCHEMBL8620628 0.81 TP53 (0.55) POLBLMNAMAPTTP53THRB
SCHEMBL6465397 0.81 CA1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL6462883 0.79 PTGES (0.52) LMNA
SCHEMBL6467690 0.78 KMT2A (0.51) CA12CA1CA2CA9ALDH1A1
SCHEMBL27679 0.77 LMNA (0.54) LMNAMAPTTP53THRBKDM4E
SCHEMBL6244071 0.76 KMT2A (0.57) CA12CA1CA2CA9MAPT
SCHEMBL8837714 0.76 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL6529186 0.75 CA1 (0.51) CA12CA1CA2CA9KMT2A
SCHEMBL6466821 0.75 KMT2A (0.53) CA12CA1CA2CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed