Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.40 |
| ▸ | IL1RN | P18510 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466904 | 0.88 | DAGLA (0.50) | XDHDAGLAFAAHCES1ELANE | |
| SCHEMBL6466056 | 0.85 | DAGLA (0.45) | XDHDAGLAFAAHCES1CTSS | |
| SCHEMBL6463414 | 0.81 | CTSS (0.44) | XDHDAGLAFAAHCES1CTSS | |
| SCHEMBL6468626 | 0.81 | CTSS (0.44) | XDHDAGLAFAAHCES1CTSS | |
| SCHEMBL6463425 | 0.80 | DAGLA (0.43) | XDHDAGLAFAAHCES1CTSS | |
| SCHEMBL7045318 | 0.79 | CTSS (0.45) | XDHDAGLAFAAHCES1CTSS | |
| SCHEMBL5523159 | 0.78 | DAGLA (0.56) | XDHDAGLAFAAHCES1ELANE | |
| SCHEMBL6464297 | 0.78 | DAGLA (0.44) | XDHDAGLAFAAHCES1ELANE | |
| SCHEMBL6467423 | 0.75 | XDH (0.44) | XDHDAGLARAB9A | |
| SCHEMBL6466213 | 0.74 | CTSL (0.45) | XDHDAGLAFAAHCES1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |