Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PRSS8 | Q16651 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466904 | 0.90 | DAGLA (0.50) | DAGLAFAAHCES1XDHMAPT | |
| SCHEMBL6463425 | 0.85 | DAGLA (0.43) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6465885 | 0.85 | XDH (0.47) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6463414 | 0.78 | CTSS (0.44) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6468626 | 0.78 | CTSS (0.44) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6464297 | 0.77 | DAGLA (0.44) | DAGLAFAAHCES1XDHPRSS8 | |
| SCHEMBL7048981 | 0.76 | DAGLA (0.45) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL5523159 | 0.76 | DAGLA (0.56) | DAGLAFAAHCES1XDHKDM4E | |
| SCHEMBL7181300 | 0.76 | CTSS (0.47) | DAGLAFAAHCES1XDHCTSS | |
| SCHEMBL6466058 | 0.75 | FAAH (0.49) | DAGLAFAAHCES1XDHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |