Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043318 | 0.91 | PPARG (0.34) | FAAHCES1DAGLAPPARGXDH | |
| SCHEMBL6062665 | 0.78 | MTNR1A (0.35) | FAAHCES1DAGLAPTPN1PTPN2 | |
| SCHEMBL6462512 | 0.73 | CTSS (0.40) | FAAHCES1DAGLALMNAHTT | |
| SCHEMBL6462741 | 0.72 | FAAH (0.36) | FAAHCES1DAGLAPTPN1PTPN2 | |
| SCHEMBL7049306 | 0.71 | DAGLA (0.44) | FAAHCES1DAGLALMNAHTT | |
| SCHEMBL6466202 | 0.71 | LMNA (0.36) | FAAHCES1DAGLALMNAHTT | |
| SCHEMBL6467037 | 0.70 | FAAH (0.36) | FAAHCES1DAGLALMNATP53 | |
| SCHEMBL7049542 | 0.69 | MAPT (0.40) | PTPN1PTPN2LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6465937 | 0.69 | FAAH (0.35) | FAAHCES1DAGLAPTPN1PTPN2 | |
| SCHEMBL7049043 | 0.67 | MAPT (0.38) | LMNAHTTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |