Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | GMNN | O75496 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14963619 | 0.77 | ALDH1A1 (0.46) | LMNASMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL6466859 | 0.77 | ALDH1A1 (0.48) | LMNAALDH1A1HSD17B10ALOX15CYP1A2 | |
| SCHEMBL16791320 | 0.75 | LMNA (0.37) | LMNASMN1; SMN2ALOX15TSHRMMP12 | |
| SCHEMBL9863149 | 0.75 | PAM (0.59) | LMNAALDH1A1CYP1A2MAPK1GMNN | |
| SCHEMBL28058899 | 0.73 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL9234611 | 0.73 | SMN1; SMN2 (0.38) | LMNASMN1; SMN2ALDH1A1ALOX15CYP1A2 | |
| SCHEMBL2466001 | 0.73 | TDP1 (0.42) | LMNASMN1; SMN2ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL9019752 | 0.72 | ALDH1A1 (0.45) | LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL27872257 | 0.71 | ALDH1A1 (0.39) | LMNASMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9019745 | 0.71 | ALDH1A1 (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014954-A1 | Pyrrole synthesis | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| EP-1451179-A1 | PYRROLE SYNTHESIS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003044011-A1 | PYRROLE SYNTHESIS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014954-A1 | Pyrrole synthesis | PNPO, PPOX, DHPS | LMNA 4840/4885SMN1; SMN2 3800/4885ALDH1A1 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.