Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TMPRSS11D | O60235 | 3/20 | 0.33 |
| ▸ | CTRL | P40313 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046552 | 0.90 | ATM (0.33) | SMN1; SMN2 | |
| SCHEMBL6467733 | 0.84 | ALDH1A1 (0.36) | KMT2AHPGDMEN1CYP2C19POLB | |
| SCHEMBL6466197 | 0.77 | FAAH (0.36) | HTTSMN1; SMN2 | |
| SCHEMBL7466136 | 0.77 | FAAH (0.36) | HTTSMN1; SMN2 | |
| SCHEMBL7044233 | 0.74 | ATM (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6063677 | 0.73 | ALOX12 (0.46) | KMT2ACYP2C19ALDH1A1TSHR | |
| SCHEMBL6466391 | 0.72 | LMNA (0.35) | KMT2ATMPRSS11DCTRLHPGDCYP2C19 | |
| SCHEMBL7575216 | 0.71 | FAAH (0.36) | HPGDPOLBHTTSMN1; SMN2 | |
| SCHEMBL6467033 | 0.71 | FAAH (0.36) | HPGDPOLBHTTSMN1; SMN2 | |
| SCHEMBL6463146 | 0.71 | ATM (0.32) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |