Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 4/20 | 0.31 |
| ▸ | METAP1 | P53582 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355953 | 0.82 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL8846301 | 0.82 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL3314941 | 0.79 | ALOX15 (0.44) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL27842102 | 0.77 | SMN1; SMN2 (0.40) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL27642794 | 0.76 | TET2 (0.54) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL8100254 | 0.76 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KMT2APOLBLMNA | |
| SCHEMBL9979696 | 0.76 | GPR84 (0.42) | L3MBTL1ALDH1A1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL31163980 | 0.74 | — | — | |
| SCHEMBL6515451 | 0.73 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1POLBLMNAHSD17B10 | |
| SCHEMBL820658 | 0.73 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1POLBLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014954-A1 | Pyrrole synthesis | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-20 | — | — | US | disclosed |
| EP-1451179-A1 | PYRROLE SYNTHESIS | Ciba SC Holding AG (CH) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003044011-A1 | PYRROLE SYNTHESIS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014954-A1 | Pyrrole synthesis | PNPO, PPOX, DHPS | L3MBTL1 4884/4885ALDH1A1 511/4885KMT2A 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.