Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12106076 | 0.82 | HTT (0.62) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL7869978 | 0.82 | HTT (0.62) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL6470799 | 0.79 | KDM4E (0.66) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL947975 | 0.79 | HSD11B1 (0.63) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL7075505 | 0.78 | HSD11B1 (0.62) | HSD11B1HTTNPSR1KDM4EALDH1A1 | |
| SCHEMBL7870815 | 0.77 | HTT (0.64) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL12103715 | 0.77 | HTT (0.59) | HSD11B1HTTNPSR1KDM4EKMT2A | |
| SCHEMBL11526951 | 0.76 | THRB (0.67) | KMT2APAX8GSK3BPTPN1 | |
| SCHEMBL1001018 | 0.76 | HSD11B1 (0.69) | HSD11B1HTTNPSR1KDM4EALDH1A1 | |
| SCHEMBL7866978 | 0.76 | KMT2A (0.60) | HSD11B1HTTNPSR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110955-A1 | SUBSTITUTED ACETOPHENOME AS MS REAGENTS | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2005-11-24 | — | — | WO | disclosed |