Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468172 | 0.84 | KMT2A (0.48) | ALDH1A1PGRGAAKDM4EBCL2L1 | |
| SCHEMBL11866798 | 0.77 | CA1 (0.44) | ALDH1A1TSHRKDM4E | |
| SCHEMBL3949200 | 0.73 | MEN1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL5744702 | 0.72 | KMT2A (0.46) | ALDH1A1PGRGAA | |
| SCHEMBL3661884 | 0.71 | BCL2L1 (0.45) | NR3C1PGRNR3C2BCL2L1 | |
| SCHEMBL3216971 | 0.70 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL571172 | 0.69 | MAOA (0.46) | ALDH1A1MTNR1AMTNR1BMAOAMAOB | |
| SCHEMBL4735838 | 0.69 | BCL2L1 (0.45) | MAOAMAOBBCL2L1 | |
| SCHEMBL7144290 | 0.68 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2BCAT1MTNR1AMTNR1B | |
| SCHEMBL20242664 | 0.66 | CA1 (0.58) | ALDH1A1SMN1; SMN2BCAT1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |