Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27708472 | 0.80 | PKM (0.39) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL27323086 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10GAAPKM | |
| SCHEMBL4672818 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10GAAPKM | |
| Alcohol SCHEMBL12986864 | 0.78 | GAA (0.50) | ALDH1A1LMNAHSD17B10GAATSHR | |
| SCHEMBL2403192 | 0.77 | GAA (0.52) | ALDH1A1LMNAHSD17B10GAATSHR | |
| SCHEMBL29135298 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10GAAPKM | |
| SCHEMBL20621933 | 0.75 | PKM (0.37) | ALDH1A1LMNAHSD17B10PKMKDM4E | |
| SCHEMBL262119 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10GAAPKM | |
| SCHEMBL556528 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10GAAPKM | |
| SCHEMBL9416752 | 0.73 | CYP4F2 (0.44) | ALDH1A1LMNAHSD17B10GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595466-B2 | NKR variants for increased production of isobutanol | GEVO, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| WO-2025049848-A2 | PROTEASES AND ALDC ENZYMES FOR BEER HAZE AND DIACETYL REDUCTION | INTERNATIONAL N&H DENMARK APS (DK) | 2025-03-06 | — | — | WO | disclosed |
| US-20230332130-A1 | ACETOLACTATE DECARBOXYLASE | INTERNATIONAL N&H DENMARK APS (DK) | 2023-10-19 | — | — | US | disclosed |
| US-20230295601-A1 | ALDC PRODUCTION METHODS | INTERNATIONAL N&H DENMARK APS (DK) | 2023-09-21 | — | — | US | disclosed |
| CN-107636151-B | Acetolactate decarboxylase | 杜邦营养生物科学有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-4155399-A1 | ACETOLACTATE DECARBOXYLASE | DuPont Nutrition Biosciences ApS (DK) | 2023-03-29 | — | — | EP | disclosed |
| US-20230087872-A1 | NOVEL NKR VARIANTS FOR INCREASED PRODUCTION OF ISOBUTANOL | GEVO, INC. | 2023-03-23 | — | — | US | disclosed |
| US-11578316-B2 | Acetolactate decarboxylase variants having improved specific activity | DUPONT NUTRITION BIOSCIENCES APS (DK) | 2023-02-14 | — | — | US | disclosed |
| EP-4114917-A1 | NOVEL NKR VARIANTS FOR INCREASED PRODUCTION OF ISOBUTANOL | GEVO, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| EP-3298138-B1 | ACETOLACTATE DECARBOXYLASE | DUPONT NUTRITION BIOSCI APS (DK) | 2022-08-10 | — | — | EP | disclosed |
| US-20110201090-A1 | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids | GEVO, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110201072-A1 | Modified alcohol dehydrogenases for the production of fuels and chemicals | GEVO, INC. (US) | 2011-08-18 | — | — | US | disclosed |
| US-7910342-B2 | Transgenic escherichia for use as bioreactor in conversion of acetolactate to dihydroxy-isovalerate; fuel additive; feedstock chemical in plastics; food and flavorings | BUTAMAX(TM) ADVANCED BIOFUELS LLC (US) | 2011-03-22 | — | — | US | disclosed |
| EP-2222841-A2 | KETOL-ACID REDUCTOISOMERASE USING NADH | ButamaxTM Advanced Biofuels LLC (US) | 2010-09-01 | — | — | EP | disclosed |
| US-20100197519-A1 | KETOL-ACID REDUCTOISOMERASE USING NADH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-05 | — | — | US | disclosed |
| EP-2134849-A2 | FERMENTIVE PRODUCTION OF ISOBUTANOL USING HIGHLY ACTIVE KETOL-ACID REDUCTOISOMERASE ENZYMES | E. I. Du Pont de Nemours and Company (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009085953-A2 | KETOL-ACID REDUCTOISOMERASE USING NADH | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090163376-A1 | KETOL-ACID REDUCTOISOMERASE USING NADH | E.I. DU PONT DE NEMOURS AND COMPANY | 2009-06-25 | — | — | US | disclosed |
| WO-2008130995-A2 | FERMENTIVE PRODUCTION OF ISOBUTANOL USING HIGHLY ACTIVE KETOL-ACID REDUCTOISOMERASE ENZYMES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080261230-A1 | FERMENTIVE PRODUCTION OF ISOBUTANOL USING HIGHLY ACTIVE KETOL-ACID REDUCTOISOMERASE ENZYMES | GEVO, INC. | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595466-B2 | NKR variants for increased production of isobutanol | TKT, DCXR, AKR1C1 | ALDH1A1 527/4885LMNA 3097/4885HSD17B10 169/4885 |
| US-20100197519-A1 | KETOL-ACID REDUCTOISOMERASE USING NADH | COASY, ME1, ADH7 | ALDH1A1 513/4885LMNA 3977/4885HSD17B10 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.