SCHEMBL647098

SCHEMBL647098

Cc1ccnc(-c2cc(C(=O)O)ccn2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JMJD6 Q6NYC1 1/20 0.66
KDM4C Q9H3R0 9/20 0.65
KDM5C P41229 7/20 0.65
KDM2A Q9Y2K7 5/20 0.65
KDM3A Q9Y4C1 5/20 0.65
KDM4E B2RXH2 5/20 0.65
KDM6B O15054 4/20 0.65
KDM4A O75164 6/20 0.64
CCR1 P32246 1/20 0.63
CCR5 P51681 1/20 0.63
CCR8 P51685 1/20 0.63
KDM5B Q9UGL1 8/20 0.62
KDM4B O94953 3/20 0.62
P4HA1 P13674 1/20 0.62
KDM5A P29375 5/20 0.57
KDM2B Q8NHM5 2/20 0.56
TET3 O43151 1/20 0.53
BBOX1 O75936 1/20 0.53
ALDH1A1 P00352 1/20 0.53
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421652 1.00 JMJD6 (0.66) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL7459447 0.98 JMJD6 (0.64) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL38661978 0.93 KDM5B (0.60) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL8572040 0.93 KDM5B (0.60) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL12993110 0.93 KDM5B (0.60) JMJD6KDM4CKDM5CKDM2AKDM3A
Dipyridyl SCHEMBL3947377 0.91 KDM4C (0.82) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL12992875 0.89 CCR1 (0.59) JMJD6KDM4CKDM5CKDM2AKDM3A
Dipyridyl SCHEMBL3957155 0.89 KDM4C (0.79) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL70700 0.88 KDM4C (0.78) JMJD6KDM4CKDM5CKDM2AKDM3A
SCHEMBL29407015 0.88 KDM4C (0.78) JMJD6KDM4CKDM5CKDM2AKDM3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117894971-B Glassy metal organic framework material modified ternary positive electrode material, and preparation method and application thereof 中南大学 2024-06-04 CN claimed
CN-117894971-A Glassy metal organic framework material modified ternary positive electrode material, and preparation method and application thereof 中南大学 2024-04-16 CN claimed
US-20150293108-A1 MEMBRANE STAINING DYES CONTAINING PHOSPHORESCENT TRANSITION METAL POLYPYRIDINE COMPLEXES CITY UNIVERSITY OF HONG KONG (HK) 2015-10-15 US claimed
US-12636366-B2 Ruthenium (II) complexes and conjugates thereof for use as photosensitizer agent in photodynamic therapy ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS (FR) 2026-05-26 US disclosed
CN-117894971-B Glassy metal organic framework material modified ternary positive electrode material, and preparation method and application thereof 中南大学 2024-06-04 CN disclosed
CN-117894971-A Glassy metal organic framework material modified ternary positive electrode material, and preparation method and application thereof 中南大学 2024-04-16 CN disclosed
CN-116936723-A Ultrathin crack-free metal-organic framework @ metal zinc and preparation method and application thereof 中南大学 2023-10-24 CN disclosed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO disclosed
US-20220296711-A1 Ruthenium (II) Complexes and Conjugates Thereof for Use as Photosensitizer Agent in Photodynamic Therapy UNIVERSITY OF ZÜRICH (CH) 2022-09-22 US disclosed
EP-3986904-A1 RUTHENIUM (II) COMPLEXES AND CONJUGATES THEREOF FOR USE AS PHOTOSENSITIZER AGENT IN PHOTODYNAMIC THERAPY Paris Sciences et Lettres (FR) 2022-04-27 EP disclosed
WO-2020260424-A1 RUTHENIUM (II) COMPLEXES AND CONJUGATES THEREOF FOR USE AS PHOTOSENSITIZER AGENT IN PHOTODYNAMIC THERAPY PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2020-12-30 WO disclosed
EP-1767588-A1 DYE AND DYE-SENSITIZED SOLAR CELL JSR Corporation (JP) 2007-03-28 EP disclosed
US-20040146895-A1 Luminescent metal ion complexes BIOSEARCH TECHNOLOGIES, INC. 2004-07-29 US disclosed
WO-2004037907-A2 LUMINESCENT METAL ION COMPLEXES BIOSEARCH TECHNOLOGIES, INC. (US) 2004-05-06 WO disclosed
US-20020177695-A1 Nucleic acid probes and methods DUKE UNIVERSITY 2002-11-28 US disclosed
US-6288221-B1 REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES DUKE UNIVERSITY 2001-09-11 US disclosed
US-6187928-B1 TREATING FUNGAL DISEASES THE ROCKEFELLER UNIVERSITY 2001-02-13 US disclosed
US-6087510-A Method of use of imidazolium cations THE ROCKEFELLER UNIVERSITY (US) 2000-07-11 US disclosed
US-5969150-A FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES THE ROCKEFELLER UNIVERSITY (US) 1999-10-19 US disclosed
US-5874587-A FLUORESCENCE THE ROCKEFELLER UNIVERSITY (US) 1999-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150293108-A1 MEMBRANE STAINING DYES CONTAINING PHOSPHORESCENT TRANSITION METAL POLYPYRIDINE COMPLEXES PHOSPHO1, PTBP1, PTDSS1 JMJD6 3550/4885KDM4C 4268/4885KDM5C 4097/4885
US-20040146895-A1 Luminescent metal ion complexes SLC30A6, SLC39A14, SLC39A3 JMJD6 2612/4885KDM4C 2107/4885KDM5C 2475/4885
US-20220296711-A1 Ruthenium (II) Complexes and Conjugates Thereof for Use as Photosensitizer Agent in Photodynamic Therapy ANXA5, CD47, SPR JMJD6 4426/4885KDM4C 4583/4885KDM5C 4576/4885
US-12636366-B2 Ruthenium (II) complexes and conjugates thereof for use as photosensitizer agent in photodynamic therapy FABP2, APC, TP53 JMJD6 4844/4885KDM4C 4830/4885KDM5C 4861/4885
US-20020177695-A1 Nucleic acid probes and methods NUDT1, NT5C3B, NT5C2 JMJD6 3806/4885KDM4C 3348/4885KDM5C 3569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.