Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048644 | 0.83 | FAAH (0.47) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6462775 | 0.83 | CES1 (0.47) | CES1MEN1KMT2ACTSLCTSB | |
| SCHEMBL7044248 | 0.82 | CTSL (0.49) | CTSLCTSBCTSS | |
| SCHEMBL6468629 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6465141 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6463419 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL7045305 | 0.80 | DAGLA (0.52) | CES1MEN1KMT2AHPGDCTSL | |
| SCHEMBL6462673 | 0.80 | MEN1 (0.42) | FAAHMEN1KMT2AHPGDCTSL | |
| SCHEMBL6464884 | 0.80 | CTSS (0.49) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL7045308 | 0.78 | CTSS (0.49) | MEN1KMT2ACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |