SCHEMBL7045305

SCHEMBL7045305

COC(=O)c1coc(C(=O)C(CCc2ccccc2)NC(=O)CCC2CCCCC2)n1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 5/20 0.52
CTSK P43235 3/20 0.41
CTSL P07711 2/20 0.41
CTSB P07858 2/20 0.41
CTSS P25774 2/20 0.41
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 4/20 0.38
EPHX2 P34913 1/20 0.38
CES1 P23141 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6462775 0.91 CES1 (0.47) DAGLACTSKCTSLCTSBCTSS
SCHEMBL7042158 0.82 DAGLA (0.42) DAGLAKMT2AALDH1A1TDP1MEN1
SCHEMBL6061916 0.82 DAGLA (0.42) DAGLAKMT2AALDH1A1EPHX2TDP1
SCHEMBL7043331 0.81 CMA1 (0.46) CTSKCTSLCTSBCTSS
SCHEMBL6063715 0.81 DAGLA (0.57) DAGLACTSKCTSLCTSBCTSS
SCHEMBL6472183 0.80 FAAH (0.48) CTSKCTSLCTSBCTSSKMT2A
SCHEMBL6465141 0.79 CTSS (0.48) DAGLACTSKCTSLCTSBCTSS
SCHEMBL6468629 0.79 CTSS (0.48) DAGLACTSKCTSLCTSBCTSS
SCHEMBL6463419 0.79 CTSS (0.48) DAGLACTSKCTSLCTSBCTSS
SCHEMBL7049425 0.78 CTSL (0.49) CTSKCTSLCTSBCTSSKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030232864-A1 Novel Compounds and compositions as protease inhibitors AXYS PHARMACEUTICALS, INC. (US) 2003-12-18 US disclosed
US-6576630-B1 Alkanoyl substituted benzooxazoles or naphthooxazoles AXYS PHARMACEUTICALS, INC. 2003-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232864-A1 Novel Compounds and compositions as protease inhibitors SERPINB1, CTRL, CTSZ DAGLA 2304/4885CTSK 32/4885CTSL 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.