Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472183 | 0.83 | FAAH (0.48) | FAAHCES1MEN1ALDH1A1KMT2A | |
| SCHEMBL7045312 | 0.82 | CTSL (0.46) | FAAHCES1CTSLCTSBCTSS | |
| SCHEMBL7047954 | 0.82 | F11 (0.47) | FAAHCES1MEN1ALDH1A1KMT2A | |
| SCHEMBL6468629 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6463419 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6465141 | 0.81 | CTSS (0.48) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6464884 | 0.80 | CTSS (0.49) | FAAHCES1MEN1KMT2ACTSL | |
| SCHEMBL6462775 | 0.80 | CES1 (0.47) | CES1MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL6799441 | 0.79 | MEN1 (0.41) | MEN1ALDH1A1KMT2ATDP1CTSL | |
| SCHEMBL6464300 | 0.78 | CTSS (0.44) | MEN1KMT2ACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232864-A1 | Novel Compounds and compositions as protease inhibitors | SERPINB1, CTRL, CTSZ | FAAH 479/4885CES1 272/4885MEN1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.