SCHEMBL38971

SCHEMBL38971

CC(C(=O)O)=C(c1ccccc1C(C)C)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
ALOX15 P16050 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.40
GABRA1 P14867 3/20 0.39
GABRB2 P47870 2/20 0.39
BCL2 P10415 2/20 0.38
MCL1 Q07820 1/20 0.38
GABRB1 P18505 2/20 0.38
GAA P10253 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
FAAH O00519 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
GABRG2 P18507 1/20 0.36
PTGS1 P23219 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355233 0.80 LMNA (0.41) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL9355234 0.80 LMNA (0.41) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL4884737 0.78 KCNK3 (0.43) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL6472265 0.77 CES1 (0.45) LMNAALOX15KMT2AALDH1A1GAA
Hydrogen Peroxide SCHEMBL1652481 0.77 GABRA1 (0.48) LMNAALOX15KMT2AALDH1A1GABRA1
Hydrogen Peroxide SCHEMBL9514730 0.74 ALDH1A1 (0.59) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL254364 0.74 ALDH1A1 (0.59) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL29657201 0.74 ALDH1A1 (0.59) LMNAALOX15KMT2AALDH1A1GABRA1
SCHEMBL1635308 0.74 GABRA1 (0.50) LMNAKMT2AALDH1A1GABRA1GABRB2
SCHEMBL29567244 0.74 GABRA1 (0.50) LMNAKMT2AALDH1A1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
CN-117017794-A Water-in-oil emulsion 莱雅公司 2023-11-10 CN claimed
US-20220387290-A1 SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-12-08 US claimed
US-20220125701-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-04-28 US claimed
EP-3946642-A1 SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF ISP Investments LLC (US) 2022-02-09 EP claimed
EP-3154510-B1 COMPOSITION FOR PROTECTING KERATIN MATERIALS FROM SUN OREAL (FR) 2022-01-19 EP claimed
US-20210338539-A1 LAMELLAR GEL BASED PERSONAL CARE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC 2021-11-04 US claimed
EP-2701670-B1 CLEAR WET SUN-CARE SPRAYS AND GELS ISP INVESTMENTS LLC (US) 2021-10-20 EP claimed
EP-3099284-B1 OIL-IN-WATER EMULSION SUNSCREEN COMPOSITION ISP INVESTMENTS LLC (US) 2021-07-28 EP claimed
WO-2020168336-A1 SUNSCREEN COMPOSITIONS AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2020-08-20 WO claimed
US-20090202461-A1 Anhydrous cosmetic composition comprising a crosslinked polyrotaxane and an oil L'OREAL S.A. (FR) 2009-08-13 US claimed
US-7534421-B2 s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2009-05-19 US claimed
EP-1353633-B1 AMPHIPHILIC POLYMER-BASED PHOTOPROTECTIVE COMPOSITIONS OREAL (FR) 2008-05-28 EP claimed
US-20080008669-A1 Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds L'OREAL (FR) 2008-01-10 US claimed
US-20070218022-A1 Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds L'OREAL, PARIS, FRANCE 2007-09-20 US claimed
EP-1815885-A2 Compositions containing a UV-B filter of the cinnamic acid ester type and a s-triazine derivative; process of photostabilising a UV-B filter of the cinnamic acid ester type L'Oréal (FR) 2007-08-08 EP claimed
EP-1815884-A2 Compositions containing an UV-B filter of the cinnamic acid ester type, a UV-A filter of the dibenzoylmethane type and a derivative of s-triazine; process of photostabilisation L'Oréal (FR) 2007-08-08 EP claimed
US-20060034791-A1 Cosmetic composition comprising a silicone polymer L'OREAL (FR) 2006-02-16 US claimed
US-6955803-B2 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers L'OREAL (FR) 2005-10-18 US claimed
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers SOCIETE L'OREAL, S.A. (FR) 2004-04-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218022-A1 Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds NISCH, SUN2, CDC73 LMNA 849/4885ALOX15 941/4885KMT2A 2415/4885
US-20040062728-A1 Photoprotective compositions comprising sulfonic/hydrophobic amphiphilic polymers CUTA, PCNA, DSG1 LMNA 224/4885ALOX15 611/4885KMT2A 3149/4885
US-20080008669-A1 Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds NISCH, SUN2, ERCC5 LMNA 862/4885ALOX15 1199/4885KMT2A 2590/4885
US-20060034791-A1 Cosmetic composition comprising a silicone polymer CUTA, GLA, LAGE3 LMNA 341/4885ALOX15 1481/4885KMT2A 2871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.