Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | PTGIR | P43119 | 5/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482645 | 0.85 | OPRD1 (0.35) | KCNH2HRH3PTGIROPRD1 | |
| SCHEMBL14972859 | 0.78 | CNR1 (0.34) | CYP19A1KCNH2HRH3F10 | |
| SCHEMBL6475851 | 0.68 | MAPK14 (0.39) | OPRD1 | |
| SCHEMBL5531063 | 0.63 | MEN1 (0.36) | PDE4A | |
| SCHEMBL5533097 | 0.61 | PDE4A (0.38) | PDE4A | |
| SCHEMBL3846422 | 0.61 | TUBB4A (0.53) | F10PDE4A | |
| SCHEMBL3849945 | 0.60 | ALDH1A1 (0.46) | CYP19A1 | |
| SCHEMBL5095886 | 0.59 | NR4A2 (0.51) | KCNH2HRH3 | |
| SCHEMBL1335750 | 0.59 | MAPK14 (0.54) | CHRM1CHRM3 | |
| SCHEMBL17956236 | 0.59 | CNR1 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919344-B2 | N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action | ASTA MEDICA, AKTIENGESELLSCHAFT (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6344467-B1 | ANTIASTHMATIC, ANTIALLERGIC AND IMMUNOSUPPRESSANT/IMMUNOMODULATING PROPERTIES | ASTA MEDICA AG (DE) | 2002-02-05 | — | — | US | disclosed |