Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531063 | 0.87 | MEN1 (0.36) | SERPINE1KDM4ENFATC1GSK3BDYRK1A | |
| SCHEMBL5533097 | 0.82 | PDE4A (0.38) | KDM4EALDH1A1NFATC1GSK3BDYRK1A | |
| SCHEMBL6474711 | 0.78 | CYP19A1 (0.38) | F10KCNH2HRH3CYP19A1 | |
| SCHEMBL6699595 | 0.70 | THRB (0.47) | TP53ALDH1A1 | |
| SCHEMBL3846422 | 0.67 | TUBB4A (0.53) | CNR1CNR2F10SERPINE1PLA2G4A | |
| SCHEMBL6579228 | 0.66 | TUBB4A (0.53) | CNR1CNR2TP53KDM4EALDH1A1 | |
| SCHEMBL6482645 | 0.65 | OPRD1 (0.35) | KCNH2HRH3KDM4EALDH1A1 | |
| SCHEMBL6222754 | 0.59 | PDE4A (0.49) | CNR1CNR2TP53ALDH1A1NFATC1 | |
| SCHEMBL3846423 | 0.59 | ROCK2 (0.43) | TP53 | |
| SCHEMBL8418175 | 0.58 | YES1 (0.51) | RXFP1SERPINE1NFATC1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-B1 | PARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INT (US) | 2013-05-29 | — | — | EP | claimed |