Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482628 | 0.89 | BCL6 (0.44) | SCN5ASCN9AAGPAT2AURKASLC6A2 | |
| SCHEMBL6474559 | 0.87 | GAA (0.43) | SCN5ASCN9AAGPAT2SLC6A2SLC6A4 | |
| SCHEMBL5204622 | 0.82 | SCN9A (0.51) | SCN5ASCN9AAURKASLC6A2BCL6 | |
| Hydrochloric Acid SCHEMBL5203439 | 0.81 | SCN9A (0.50) | SCN5ASCN9AAURKASLC6A2BCL6 | |
| SCHEMBL6474012 | 0.79 | BCL6 (0.52) | SCN5ASCN9AAURKAMEN1MAPT | |
| SCHEMBL5207953 | 0.79 | SLC6A2 (0.44) | SLC6A2SLC6A4CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6481407 | 0.78 | AURKA (0.47) | SCN5ASCN9AAURKAMEN1MAPT | |
| SCHEMBL6480285 | 0.75 | AURKA (0.53) | AURKAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL1376409 | 0.75 | MERTK (0.39) | SLC6A2SLC6A4CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1376410 | 0.75 | MERTK (0.39) | SLC6A2SLC6A4CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |