Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202344 | 0.88 | SCN9A (0.47) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6474741 | 0.87 | SCN5A (0.42) | MAPTSLC6A2SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL6480001 | 0.82 | MAPT (0.49) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6473796 | 0.81 | MAPT (0.51) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL6473728 | 0.81 | MAPT (0.50) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL5207953 | 0.77 | SLC6A2 (0.44) | ALDH1A1SLC6A2SLC6A4CYP1A2CYP3A4 | |
| SCHEMBL5204470 | 0.77 | MEN1 (0.42) | ALDH1A1MAPTLMNACASP1CASP7 | |
| SCHEMBL6482628 | 0.76 | BCL6 (0.44) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL3250337 | 0.74 | ALDH1A1 (0.43) | GAAALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL1376410 | 0.74 | MERTK (0.39) | LMNAHPGDSMN1; SMN2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |