Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | CBR1 | P16152 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | STK39 | Q9UEW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474741 | 0.89 | SCN5A (0.42) | BCL6AURKAMAPTNR1I2SLC6A2 | |
| SCHEMBL6474012 | 0.86 | BCL6 (0.52) | BCL6AURKAMAPTLMNAGAA | |
| SCHEMBL5204622 | 0.84 | SCN9A (0.51) | BCL6AURKAADORA3SLC6A2KCNH2 | |
| Hydrochloric Acid SCHEMBL5203439 | 0.83 | SCN9A (0.50) | BCL6AURKAADORA3SLC6A2KCNH2 | |
| SCHEMBL5203455 | 0.78 | TTR (0.40) | BCL6MAPTHPGDTTRNR1I2 | |
| SCHEMBL6474471 | 0.77 | BCL6 (0.49) | BCL6AURKAMAPTLMNAGAA | |
| SCHEMBL5204470 | 0.76 | MEN1 (0.42) | BCL6MAPTLMNAALDH1A1POLB | |
| SCHEMBL5204374 | 0.76 | SCN9A (0.44) | BCL6MAPTKCNH2SCN9ASCN5A | |
| SCHEMBL6474559 | 0.76 | GAA (0.43) | MAPTHPGDLMNASLC6A2SLC6A3 | |
| SCHEMBL6480285 | 0.75 | AURKA (0.53) | AURKAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |