Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 5/20 | 0.45 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482628 | 0.86 | BCL6 (0.44) | BCL6KCNH2SCN5ASCN9AAURKA | |
| SCHEMBL6474471 | 0.84 | BCL6 (0.49) | BCL6SCN5ASCN9AAURKATTBK1 | |
| SCHEMBL5204622 | 0.81 | SCN9A (0.51) | BCL6KCNH2SCN5ASCN9AAURKA | |
| Hydrochloric Acid SCHEMBL5203439 | 0.81 | SCN9A (0.50) | BCL6KCNH2SCN5ASCN9AAURKA | |
| SCHEMBL6474741 | 0.79 | SCN5A (0.42) | BCL6KCNH2SCN5ASCN9AAURKA | |
| SCHEMBL6480285 | 0.77 | AURKA (0.53) | AURKATTBK1TTBK2MAPTALDH1A1 | |
| SCHEMBL6472908 | 0.77 | TTBK1 (0.43) | BCL6KCNH2SCN5ASCN9AAURKA | |
| SCHEMBL6481407 | 0.77 | AURKA (0.47) | BCL6KCNH2SCN5ASCN9AAURKA | |
| SCHEMBL6480339 | 0.74 | MAPT (0.44) | AURKAMAPTGAAALDH1A1MEN1 | |
| SCHEMBL5203804 | 0.73 | MAPK14 (0.47) | BCL6FLT3GSK3BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916820-B1 | Neurotrophic substituted pyrimidines | KRENITSKY PHARMACEUTICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |