Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480023 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL7961902 | 0.88 | GPR88 (0.42) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL8654380 | 0.87 | HTR1E (0.34) | ALDH1A1CNR2NPSR1SMN1; SMN2 | |
| SCHEMBL6475744 | 0.87 | POLB (0.39) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6482465 | 0.86 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6483796 | 0.84 | SMYD3 (0.37) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6482458 | 0.83 | SMYD3 (0.36) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6474821 | 0.82 | NPSR1 (0.40) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6483628 | 0.82 | CNR2 (0.37) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6474841 | 0.82 | LPAR1 (0.37) | CNR2NPSR1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | ALDH1A1 792/4885CYP3A4 120/4885CYP2D6 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.