Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 2/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481238 | 0.91 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL7950103 | 0.88 | GPR88 (0.41) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL8652084 | 0.88 | HTR1E (0.36) | ALDH1A1SMN1; SMN2LPAR1NPSR1 | |
| SCHEMBL6475744 | 0.86 | POLB (0.39) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6483536 | 0.86 | FAAH (0.43) | FAAHTRPV1NPSR1 | |
| SCHEMBL6475667 | 0.86 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2D6MAPK1CYP2C19 | |
| SCHEMBL6482748 | 0.85 | FAAH (0.45) | FAAHTRPV1NPSR1 | |
| SCHEMBL6475256 | 0.85 | FAAH (0.45) | FAAHTRPV1NPSR1 | |
| SCHEMBL6475228 | 0.85 | FAAH (0.45) | FAAHTRPV1NPSR1 | |
| SCHEMBL6474520 | 0.83 | LPAR1 (0.40) | ALDH1A1FAAHLPAR1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6939888-B2 | 1-H-3-arylpirrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | FISCHER REINER (DE) | 2004-01-29 | — | — | US | disclosed |
| US-6472419-B1 | 1-H-3-aryl-pyrrolidine-2, 4-dione derivatives as pest-control agents | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019061-A1 | 1-H-3-arylpirrolidine-2,4-dione derivatives | PRXL2A, DDT, CYP4B1 | ALDH1A1 792/4885CYP3A4 120/4885CYP2D6 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.