Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6269419 | 0.98 | POLB (0.53) | POLBSIGMAR1CASRSMN1; SMN2ADRB2 | |
| SCHEMBL5681763 | 0.85 | POLB (0.68) | POLBSIGMAR1CASRSMN1; SMN2ADRB2 | |
| Hydrochloric Acid SCHEMBL6274840 | 0.84 | MEN1 (0.41) | POLBSMN1; SMN2ADRB2ITGB1ITGA5 | |
| Hydrochloric Acid SCHEMBL7770226 | 0.84 | POLB (0.43) | POLBSIGMAR1SMN1; SMN2ADRB2ITGB1 | |
| Hydrochloric Acid SCHEMBL6268364 | 0.83 | PNMT (0.44) | POLBEGFRALDH1A1IDO1 | |
| SCHEMBL6490146 | 0.82 | CASR (0.53) | CASRADRB2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6270344 | 0.82 | CYP1A2 (0.43) | POLBMEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6273752 | 0.81 | ALDH1A1 (0.40) | POLBSMN1; SMN2ITGB1ITGA5GAA | |
| Hydrochloric Acid SCHEMBL6274790 | 0.79 | MITF (0.43) | POLBSMN1; SMN2GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6269507 | 0.79 | TAAR1 (0.36) | POLBSMN1; SMN2ADRB2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951574-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | LIM MU-ILL (US) | 2004-12-23 | — | — | US | disclosed |
| US-6780999-B2 | Primary intermediates for oxidative coloration of hair | THE PROCTER & GAMBLE COMPANY | 2004-08-24 | — | — | US | disclosed |
| EP-1353895-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002058632-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLARIOL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040255403-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | POLB 247/4885SIGMAR1 1872/4885CASR 4858/4885 |
| US-20020144357-A1 | Primary intermediates for oxidative coloration of hair | COX5A, CYC1, MT-CO1 | POLB 247/4885SIGMAR1 1872/4885CASR 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.