Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 9/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 6/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6175385 | 0.81 | SIGMAR1 (0.64) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11782242 | 0.80 | DRD2 (0.66) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3454609 | 0.78 | SIGMAR1 (1.00) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3976547 | 0.78 | ALDH1A1 (1.00) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14410956 | 0.78 | HTR1A (1.00) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31513986 | 0.78 | ALDH1A1 (1.00) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6597710 | 0.77 | PPARG (0.47) | SIGMAR1HTR1AMAPTDRD2DRD3 | |
| SCHEMBL10483006 | 0.77 | PHGDH (0.53) | SIGMAR1HTR1AALDH1A1MAPTTSHR | |
| Hydrochloric Acid SCHEMBL15263292 | 0.77 | ALDH1A1 (0.98) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6619322 | 0.74 | ALDH1A1 (0.71) | SIGMAR1HTR1AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209216-A1 | Phenyl-and pyridyl-diazaheterocycles having a tnf-modulating activity | SANOFI-AVENTIS (FR) | 2005-09-22 | — | — | US | disclosed |
| US-6893672-B2 | Peelable film and packaging made therefrom | PECHINEY EMBALLAGE FLEXIBLE EUROPE (FR) | 2005-05-17 | — | — | US | disclosed |
| US-20030064181-A1 | Peelable film and packaging made therefrom | BEMIS COMPANY, INC. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209216-A1 | Phenyl-and pyridyl-diazaheterocycles having a tnf-modulating activity | TNF, TNFRSF1A, CD40 | SIGMAR1 498/4885HTR1A 397/4885ALDH1A1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.