Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491767 | 0.86 | PTPN1 (0.50) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL8413609 | 0.84 | PTPN1 (0.48) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL1614175 | 0.84 | MAPT (0.64) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL30080217 | 0.83 | PTPN1 (0.49) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL2127382 | 0.83 | PTPN1 (0.49) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL2126462 | 0.83 | PTPN1 (0.49) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL6491145 | 0.81 | PTPN1 (0.47) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL4634025 | 0.81 | HPGD (0.54) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL29897738 | 0.81 | HPGD (0.54) | HPGDNPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL21206935 | 0.79 | MAPT (0.61) | HPGDNPC1CYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960668-B2 | Process for the production of substituted thioxanthones | GREAT LAKES (UK) LIMITED (GB) | 2005-11-01 | — | — | US | disclosed |
| US-6844343-B1 | Nitric oxide synthase inhibitors; strokes | VASOPHARM BIOTECH GMBH (DE) | 2005-01-18 | — | — | US | disclosed |
| US-20040059133-A1 | Process for the production of substituted thioxanthones | GREAT LAKES (UK) LIMITED (GB) | 2004-03-25 | — | — | US | disclosed |
| EP-1380580-A1 | An improved process for the production of subsituted thioxanthones | Great Lakes (UK) Limited (GB) | 2004-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059133-A1 | Process for the production of substituted thioxanthones | TST, MPST, DHPS | HPGD 418/4885NPC1 3660/4885CYP1A2 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.