Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 6/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176710 | 0.87 | PNMT (0.47) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| Hydrochloric Acid SCHEMBL13570531 | 0.85 | PNMT (0.45) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL30531117 | 0.84 | PRMT6 (0.44) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL16368536 | 0.84 | HDAC4 (0.47) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL25359641 | 0.84 | PRMT6 (0.44) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL1365912 | 0.83 | SIGMAR1 (0.42) | DRD2 | |
| Hydrochloric Acid SCHEMBL15922780 | 0.82 | TPSAB1 (0.43) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL8287053 | 0.82 | KMO (0.49) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| Hydrochloric Acid SCHEMBL16343416 | 0.82 | HDAC4 (0.46) | TPSAB1PNMTENPP2LOXL2PRMT6 | |
| SCHEMBL27585548 | 0.81 | TPSAB1 (0.43) | TPSAB1PNMTENPP2LOXL2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| US-20120142735-A1 | DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]- 1H-INDOL-3-YL]-METHANONES | SANOFI (FR) | 2012-06-07 | — | — | US | disclosed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142735-A1 | DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]- 1H-INDOL-3-YL]-METHANONES | CMA1, TPSB2, TPSAB1 | TPSAB1 3/4885PNMT 240/4885ENPP2 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.