SCHEMBL6488934

SCHEMBL6488934

Cc1c(C(C[C@H](C)c2ccc(O)c(C(C)(C)C)c2C)c2ccc(O)c(C(C)(C)C)c2C)ccc(O)c1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.35
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
TSHR P16473 1/20 0.30
TRPA1 O75762 1/20 0.30
LMNA P02545 1/20 0.30
CHRM1 P11229 1/20 0.30
SLC6A2 P23975 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651373 1.00 RORC (0.35) RORCCNR1CNR2TSHRTRPA1
SCHEMBL6394389 0.80 CYP2D6 (0.37) RORC
SCHEMBL1070452 0.79 TP53 (0.50) RORCCNR1CNR2
SCHEMBL30623136 0.79 TP53 (0.50) RORCCNR1CNR2
SCHEMBL9854163 0.78 RORC (0.36) RORCTSHR
SCHEMBL6020246 0.77 CA2 (0.37) TSHR
SCHEMBL25311714 0.77 PTGS2 (0.43) LMNA
SCHEMBL550440 0.72 ALDH1A1 (0.38) TSHRLMNA
SCHEMBL4483852 0.70 TRPA1 (0.44) TSHRTRPA1LMNA
SCHEMBL27340395 0.69 RORC (0.54) RORCCNR1CNR2TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120301825-A1 LAYERED STRUCTURE AND PHOTOSENSITIVE DRY FILM TO BE USED THEREFOR TAIYO HOLDINGS CO., LTD. (JP) 2012-11-29 US disclosed
US-6867250-B1 Non-yellowing ortho-dialkyl aryl substituted triazine ultraviolet light absorbers CYTEC TECHNOLOGY CORP. (US) 2005-03-15 US disclosed
EP-1375531-A1 PROCESS FOR PRODUCING VINYL POLYMER HAVING ALKENYL GROUP AT END, VINYL POLYMER, AND CURABLE COMPOSITION KANEKA CORPORATION (JP) 2004-01-02 EP disclosed
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP disclosed