Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 4/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497144 | 0.80 | LMNA (0.42) | HIF1AMAOBKDM4EALDH1A1RAB9A | |
| SCHEMBL6490670 | 0.77 | HDAC1 (0.44) | PTPN1HIF1AHDAC1KDM4EALDH1A1 | |
| SCHEMBL6490529 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6492750 | 0.72 | KDM4E (0.43) | HDAC1KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL6500991 | 0.70 | ALOX5AP (0.42) | ALDH1A1BCL2MAPTMCL1SMN1; SMN2 | |
| SCHEMBL7065211 | 0.69 | IDO1 (0.39) | HDAC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6489317 | 0.69 | MTNR1A (0.42) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27960495 | 0.69 | ALDH1A1 (0.50) | MAOBHDAC1KDM4EALDH1A1RAB9A | |
| SCHEMBL6501452 | 0.68 | IDO1 (0.41) | HDAC1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25430887 | 0.68 | PTPN1 (0.61) | PTPN1HDAC1KDM4EMCL1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | NR1H2 3132/4885NR1H3 3173/4885RXRA 2329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.