Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.45 |
| ▸ | KLK1 | P06870 | 3/20 | 0.45 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491523 | 0.92 | KIT (0.42) | PLGKLK1KLK6GCGRKIT | |
| SCHEMBL6501885 | 0.88 | GCGR (0.44) | PLGKLK1KLK6OPRL1GCGR | |
| SCHEMBL6498569 | 0.88 | ALOX15 (0.44) | PLGKLK1KLK6ALOX15GCGR | |
| SCHEMBL6502528 | 0.86 | TRPV1 (0.42) | PLGKLK1KLK6ALOX15GCGR | |
| SCHEMBL6491904 | 0.85 | ITGB1 (0.43) | PLGKLK1KLK6OPRL1GCGR | |
| SCHEMBL6490155 | 0.84 | L3MBTL1 (0.47) | ALOX15GCGRKDRKMT2AHDAC7 | |
| SCHEMBL6499114 | 0.83 | HDAC7 (0.47) | PLGKLK1KLK6OPRL1GCGR | |
| SCHEMBL6503526 | 0.81 | TRPV1 (0.43) | GCGRKDRKIT | |
| SCHEMBL6499727 | 0.81 | OPRL1 (0.43) | OPRL1GCGRKDRRAB9AKIT | |
| SCHEMBL6488561 | 0.81 | SMO (0.43) | ALOX15GCGRKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | PLG 924/4885KLK1 3176/4885KLK6 4460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.