Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 3/20 | 0.39 |
| ▸ | APOB | P04114 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501001 | 0.96 | OPRL1 (0.43) | OPRL1KITTRPV1MGAT2MTTP | |
| SCHEMBL6499275 | 0.89 | MTTP (0.47) | OPRL1KITTRPV1MGAT2MTTP | |
| SCHEMBL6491523 | 0.89 | KIT (0.42) | KITTRPV1MTTPAPOBGCGR | |
| SCHEMBL6795217 | 0.89 | SMO (0.47) | OPRL1TRPV1MTTPAPOBSMO | |
| SCHEMBL6503526 | 0.88 | TRPV1 (0.43) | KITTRPV1MTTPAPOBGCGR | |
| SCHEMBL6491904 | 0.88 | ITGB1 (0.43) | OPRL1GCGRRAB9ATP53POLB | |
| SCHEMBL6503236 | 0.88 | MAPT (0.39) | OPRL1MGAT2MTTPAPOBGCGR | |
| SCHEMBL6502528 | 0.88 | TRPV1 (0.42) | KITTRPV1MTTPAPOBGCGR | |
| SCHEMBL6500853 | 0.85 | CHRNB2 (0.42) | OPRL1MTTPAPOBGCGREGLN1 | |
| SCHEMBL6489404 | 0.85 | LMNA (0.43) | KITTRPV1MTTPAPOBGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | OPRL1 1292/4885KIT 4485/4885TRPV1 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.