Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5035778 | 0.89 | RAB9A (0.46) | MAPTRAB9ALDHAPTGER1MEN1 | |
| SCHEMBL5032527 | 0.83 | ALDH1A1 (0.46) | MAPTRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5041155 | 0.83 | CYP3A4 (0.39) | MAPTRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL6491942 | 0.82 | TSHR (0.42) | MEN1KMT2AMARS1KDM4EEIF4E | |
| SCHEMBL5034952 | 0.80 | CYP3A4 (0.46) | RAB9ALDHAPTGER1MEN1KMT2A | |
| SCHEMBL5032520 | 0.79 | LMNA (0.47) | MAPTRAB9ALDHAPTGER1MEN1 | |
| SCHEMBL5035149 | 0.79 | ALDH1A1 (0.41) | MAPTRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL5035123 | 0.77 | DHODH (0.42) | LDHAMARS1KDM4EEIF4ESMN1; SMN2 | |
| SCHEMBL5032622 | 0.76 | FLT1 (0.40) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL5032563 | 0.75 | ALDH1A1 (0.47) | MAPTPTGER1LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050153962-A1 | Thiazole derivatives | HOFFMANN-LA ROCHE INC. | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153962-A1 | Thiazole derivatives | CNR1, CNR2, GPR119 | MAPT 3183/4885RAB9A 1847/4885LDHA 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.