Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490926 | 0.94 | MAPT (0.37) | MAPK14DDR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6676731 | 0.91 | TP53 (0.40) | MAPTSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL6502051 | 0.89 | SMN1; SMN2 (0.45) | MAPK14MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6489380 | 0.89 | SMN1; SMN2 (0.42) | MAPK14DDR2MAPTSMN1; SMN2RAB9A | |
| SCHEMBL6496990 | 0.84 | RAB9A (0.37) | MAPTSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL6490483 | 0.83 | POLB (0.42) | MAPTSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL6501867 | 0.83 | TP53 (0.38) | MAPTSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL6487835 | 0.82 | HTR2C (0.48) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL6498885 | 0.82 | PPARG (0.37) | RAB9APPARGPPARATP53MEN1 | |
| SCHEMBL6495778 | 0.79 | ITGB3 (0.42) | RAB9ANPC1PPARGPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | MAPK14 3568/4885DDR2 3015/4885MAPT 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.