Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.42 |
| ▸ | ITGAV | P06756 | 5/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497772 | 0.90 | ITGB1 (0.37) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6491074 | 0.90 | PPARG (0.41) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6490709 | 0.89 | CHRNB2 (0.45) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6490926 | 0.85 | MAPT (0.37) | NPC1LMNAPKMKDM4ERAB9A | |
| SCHEMBL6533865 | 0.85 | ITGB3 (0.37) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6498885 | 0.84 | PPARG (0.37) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6487913 | 0.83 | CHRNB2 (0.43) | ITGB3ITGAVITGB1ITGA5ITGB6 | |
| SCHEMBL6496990 | 0.83 | RAB9A (0.37) | NPC1LMNAKDM4ERAB9A | |
| SCHEMBL6487835 | 0.81 | HTR2C (0.48) | NPC1LMNAPKMHTR2AHTR2C | |
| SCHEMBL6493019 | 0.79 | MAPK14 (0.37) | NPC1LMNAPPARGPPARARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | ITGB3 2225/4885ITGAV 2516/4885ITGB1 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.