Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804223 | 0.86 | CTSA (0.42) | CTSA | |
| SCHEMBL6499973 | 0.85 | PKM (0.51) | CTSAPKM | |
| SCHEMBL6176693 | 0.76 | PKM (0.44) | PKM | |
| SCHEMBL6175673 | 0.76 | CTSA (0.45) | CTSAPKM | |
| SCHEMBL6179589 | 0.76 | CTSA (0.45) | CTSAPKM | |
| SCHEMBL6177067 | 0.76 | CTSA (0.45) | CTSAPKM | |
| SCHEMBL27510388 | 0.75 | MAOB (0.53) | CTSAPKM | |
| SCHEMBL6490652 | 0.73 | ITGB3 (0.73) | — | |
| SCHEMBL6177984 | 0.72 | PKM (0.75) | PKM | |
| SCHEMBL16109287 | 0.71 | CTSA (0.58) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020123489-A1 | Benzamidine derivatives | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-09-05 | — | — | US | claimed |
| WO-2002048122-A2 | BENZAMIDINE DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-20 | — | — | WO | claimed |
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1218005-B1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1218005-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1218005-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SmithKline Beecham Corporation (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017959-A2 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123489-A1 | Benzamidine derivatives | OPRD1, OPRK1, OPRM1 | CTSA 1620/4885PKM 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.